Compare the evidence behind the orthologs.
Choose candidates and read their disease, function and phenotype annotations side by side. Every alternative remains yours to evaluate.
Annotation counts reflect coverage and curation practices. They are not similarity scores or a ranking of model organisms. Phenotypes are source text; differences do not establish functional divergence.
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Choose a gene
Select up to three candidates. The query gene is always included. Candidates are listed alphabetically; none is selected automatically.
Sources, snapshot and limitations
Ortholog candidates use the Alliance stringent subset and its DIOPT-derived integration. Support is a count of sources, not a probability. Disease counts use exact terms. Positive GO counts exclude NOT and ND; all original annotation rows remain inspectable.
gnomAD 4.1.1 values are MANE Select ENST records, joined by a unique Ensembl gene ID. Quality flags and missing or zero expected variation limit interpretation. Metrics and thresholds differ by release; older BioWeaver tools retain their separately labelled snapshots. See gnomAD's interpretation guidance.
NCBI metadata currently covers human genes. FlyBase complementation records describe curated experimental relationships; inspect the linked reference for the assay, direction and conditions. They do not establish full functional equivalence.